Taiwanese team finds cause of ovarian cancer-induced gene mutations

Focus Taiwan
Date: 2015/11/20
By: H.F. Lee and Lillian Lin

Hualien, Nov. 20 (CNA) A medical research team in Taiwan has found that follicular fluid (FF) released from ovulation can cause genetic changes related to ovarian cancer, and that the cancer-causing substance originates from the fallopian tube fimbriae rather than the ovaries.

The research report on risk factors for ovarian high-grade serous carcinoma (HGSC) compiled by the Department of Obstetrics and Gynecology of the Hualien Tzu Chi Hospital (花蓮慈濟醫院) has been published by the journal “Carcinogenesis: Integrative Cancer Research.”

Chu Tang-yuan(朱堂元), director of the hospital’s Department of Obstetrics and Gynecology, said Friday that when released from ovulation, FF, which contains high levels of reactive oxygen species (ROS), can cause mutation of the umbrella end of the fallopian tube.     [FULL  STORY]