Researchers find key to metastasis of solid cancers

PREDICTOR: Researchers said they have applied for patents in several nations, and hope the research would contribute to new cancer therapies and drugs

Taipei Times
Date: Jan 22, 2020
By: Wu Liang-yi  /  Staff reporter

After a decade of research, researchers have found a key to the metastasis of cancer, Academia

Jou Yuh-shan, left, a research fellow at Academia Sinica’s Institute of Biomedical Sciences, and postdoctoral researcher Lan Yao-tung release research results at a news conference in Taipei yesterday.
Photo: Wu Liang-yi, Taipei Times

Sinica said yesterday.

In 2018, Institute of Biomedical Sciences research fellow Jou Yuh-shan (周玉山) and postdoctoral researcher Lan Yao-tung (藍耀東), among others, discovered that the gene paraspeckle component 1 (PSPC1) is associated with cancer metastasis, the institute said.

Now they have gained a deeper understanding of the connection, it said, adding that they believe the abnormal expression of PSPC1 could turn proteins in cells “from heroes to villains,” and cause a series of carcinogenic effects, including cancer cell metastasis.

PSPC1 can control the passage of proteins between the nucleus and cytoplasm, Jou said.
[FULL  STORY]

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