CISION PR Newswire
Date: Nov 30, 2020
By: AP Biosciences, LuminX
TAIPEI, Nov. 30, 2020 /PRNewswire/ — In recent years, an increasing number of drugs have been granted breakthrough therapy designation in the United States, encouraging more companies to propose novel cancer treatment solutions. Currently, there are two companies in Taiwan that are accelerating the development of these therapies and provide innovative treatments.
AP Biosciences' target-dependent T-cell activating bi-specific antibodies
AP Biosciences and LuminX Logos
AP Biosciences (APBio) is a discovery-stage immunotherapeutic company developing mono- and bi-specific antibodies for various forms of treatment. One of the company's major products, T-Cube bsAbs, involves bi-specific antibodies that lead T cells to cancer cells. They do so by bridging the T cells to unique antigens found on the surface of cancer cells, resulting in T cell activation which kills the cancer cells.
Unlike many current immune-therapeutic drugs (which activate the immune system to combat cancer cells while inducing a cytokine storm accompanied by strong side effects), APBio's antibody drugs would benefit patients via improved specificity, leading to higher efficacy and a more favourable safety profile.
"T-Cube bi-specific antibodies activate cytotoxic and memory T cells upon binding to targeted cancer cells. In short, we're creating better antibodies for better cures," explained Dr. Jeng Her, CEO of APBio. "In the near term, we see these treatments benefiting patients with liver, kidney, and lung cancers. Superiority in efficacy, safety, and cost is what makes our solutions unique and exciting to the medical community." [FULL STORY]